A common side effect of kidney transplantation is diabetes. Diabetes mellitus after kidney transplantation is linked to greater rates of cardiovascular disease and infection, the two main killers of kidney transplant patients, as well as increased mortality and morbidity. A common side effect of kidney transplantation is diabetes. Diabetes mellitus after kidney transplantation (PTDM) is linked to greater rates of cardiovascular disease and infection, the two main killers of kidney transplant patients, as well as increased mortality and morbidity. In addition, glycemic control is often more difficult after transplantation. In addition to the increased clearance of insulin from the circulation with a newly functioning kidney transplant, immunosuppressive regimens used after transplantation have detrimental effects on pancreatic beta cell function and peripheral insulin action, which make it difficult to achieve target glucose levels and prevent the recurrence of the diabetic lesions in the transplanted kidney
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